Raman micro-spectroscopy monitoring of cytochrome c redox state in Candida utilis during cell death under low-temperature plasma-induced oxidative stress

Author:

Chen Zhu12345ORCID,Liu Jinghua12345,Tian Lijiao675ORCID,Zhang Qianqian12345,Guan Yong675,Chen Liang675,Liu Gang675,Yu Han-qing675ORCID,Tian Yangchao675,Huang Qing12345ORCID

Affiliation:

1. Key Laboratory of High Magnetic Field and Ion Beam Physical Biology

2. Hefei Institutes of Physical Science

3. Chinese Academy of Sciences

4. Hefei 230031

5. China

6. University of Science & Technology of China

7. Hefei

Abstract

Low-temperature plasma may induce oxidative stress and result in different modes of cell death, such as necrosis, apoptosis and necroptosis, which can be monitored by Raman micro-spectroscopy based on the change of cellular cytochrome c redox state.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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