Polypharmacology of andrographolide: beyond one molecule one target-Reference-Cited by-同舟云学术

Polypharmacology of andrographolide: beyond one molecule one target

Published:2021 Issue:4 Volume:38 Page:682-692
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Tran Quy T. N.¹²³⁴^ORCID,Tan W. S. Daniel⁵⁶⁷⁴^ORCID,Wong W. S. Fred⁵⁶⁷⁴⁸^ORCID,Chai Christina L. L.¹²³⁴⁹^ORCID

Affiliation:

1. Department of Pharmacy

2. Faculty of Science

3. National University of Singapore

4. Singapore

5. Department of Pharmacology

6. Yong Loo Lin School of Medicine

7. National University Health System

8. Immunology Program

9. Drug Discovery and Optimization Platform

Abstract

The ability of metabolically labile andrographolide to deliver good systemic efficacy is of great interest. This highlight provides a perspective on possible factors that may contribute to this, specifically, the polypharmacology of andrographolide.

Funder

National Research Foundation Singapore

Ministry of Education – Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NP/D0NP00049C

Reference63 articles.

1. Polypharmacology: drug discovery for the future

2. 7-epi-Clusianone, a Multi-Targeting Natural Product with Potential Chemotherapeutic, Immune-Modulating, and Anti-Angiogenic Properties

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