Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma-Reference-Cited by-同舟云学术

Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma

Published:2020 Issue:22 Volume:11 Page:5658-5668
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

An Jong Min¹²³⁴⁵,Kang Sangrim⁶⁷³⁴⁵,Huh Eugene⁸²³⁴⁵,Kim Yejin⁹¹⁰¹¹⁷¹²,Lee Dahae⁹¹⁰¹¹⁷¹²,Jo Hyejung⁹¹⁰¹¹⁷¹²,Joung Joonyoung F.¹³¹⁴¹⁵⁵^ORCID,Kim Veronica Jihyun¹⁶¹⁰¹¹⁷¹²,Lee Ji Yeoun¹⁶¹⁰¹¹⁷¹²,Dho Yun Sik¹⁷¹⁸¹¹⁷¹²,Jung Yuna¹²³⁴⁵,Hur Junho K.¹²³⁴⁵,Park Chan¹²³⁴⁵,Jung Junyang¹²³⁴⁵,Huh Youngbuhm¹²³⁴⁵,Ku Ja-Lok¹⁹²⁰¹¹⁷¹²,Kim Sojin¹⁷¹⁸¹¹⁷¹²,Chowdhury Tamrin¹⁷¹⁸¹¹⁷¹²,Park Sungnam¹³¹⁴¹⁵⁵^ORCID,Kang Jae Seung⁹¹⁰¹¹⁷¹²,Oh Myung Sook⁸²³⁴⁵^ORCID,Park Chul-Kee¹⁷¹⁸¹¹⁷¹²,Kim Dokyoung¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biomedical Science

2. Graduate School

3. Kyung Hee University

4. Seoul 02447

5. Korea

6. Department of Anatomy and Neurobiology

7. College of Medicine

8. Department of Medical Science of Meridian

9. Laboratory of Vitamin C and Antioxidant Immunology

10. Department of Anatomy and Cell Biology

11. Seoul National University

12. Seoul 03080

13. Department of Chemistry

14. Korea University

15. Seoul 02841

16. Neural Development and Anomaly Laboratory

17. Department of Neurosurgery

18. Seoul National University Hospital

19. Korean Cell Line Bank

20. Cancer Research Institute

Abstract

A fluorescent molecular probe for the identification of glioblastoma is developed. The probe allows the tracing of the cysteine (Cys) level, which is recognized as a new biomarker of GBM.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01085E

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