The neutralization of heparan sulfate by heparin-binding copolymer as a potential therapeutic target-Reference-Cited by-同舟云学术

The neutralization of heparan sulfate by heparin-binding copolymer as a potential therapeutic target

Published:2019 Issue:6 Volume:9 Page:3020-3029
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kalaska Bartlomiej¹²³⁴^ORCID,Miklosz Joanna¹²³⁴^ORCID,Kamiński Kamil⁵⁶⁷⁴,Musielak Bogdan⁵⁶⁷⁴,Yusa Shin-Ichi⁸⁹¹⁰¹¹¹²,Pawlak Dariusz¹²³⁴,Nowakowska Maria⁵⁶⁷⁴,Szczubiałka Krzysztof⁵⁶⁷⁴,Mogielnicki Andrzej¹²³⁴^ORCID

Affiliation:

1. Department of Pharmacodynamics

2. Medical University of Bialystok

3. 15-089 Bialystok

4. Poland

5. Faculty of Chemistry

6. Jagiellonian University

7. 30-387 Krakow

8. Department of Applied Chemistry

9. Graduate School of Engineering

10. University of Hyogo

11. Himeji

12. Japan

Abstract

The neutralization of heparan sulfate (HS) by a heparin-binding copolymer (HBC) could be a promising treating option for bacterial or viral infections or bleeding related to overproduction of HS in cancer or other diseases.

Funder

Narodowe Centrum Nauki

Uniwersytet Medyczny w Bialymstoku

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA09724K

Reference64 articles.

1. Anticoagulant Heparan Sulfate

2. Pathophysiology of heparan sulphate: many diseases, few drugs