Novel imidazole derivatives as potential aromatase and monoamine oxidase-B inhibitors against breast cancer-Reference-Cited by-同舟云学术

Novel imidazole derivatives as potential aromatase and monoamine oxidase-B inhibitors against breast cancer

Published:2022 Issue:16 Volume:46 Page:7442-7451
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Osmaniye Derya¹²^ORCID,Levent Serkan¹²,Sağlık Begum Nurpelin¹²^ORCID,Karaduman Abdullah Burak³,Özkay Yusuf¹²,Kaplancıklı Zafer Asım¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey

2. Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey

3. Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey

Abstract

The activity of the synthesized compounds against breast cancer was investigated. Molecular docking studies were performed against aromatase, MAO-B, and Caspase-3 enzymes.

Funder

Anadolu Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00424K

Reference47 articles.

1. Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer

2. Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation

3. Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies

4. Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors

5. Thiazole-containing compounds as therapeutic targets for cancer therapy

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