Vilsmeier cyclization of α-acetyl-α-aroyl ketene-N,S-acetals: direct and efficient synthesis of halogenated pyridin-2(1H)-ones-Reference-Cited by-同舟云学术

Vilsmeier cyclization of α-acetyl-α-aroyl ketene-N,S-acetals: direct and efficient synthesis of halogenated pyridin-2(1H)-ones

Published:2015 Issue:15 Volume:5 Page:11293-11296
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yu Haifeng¹²³⁴,Zhang Yongmei¹²³⁴,Li Tiechun¹²³⁴,Liao Peiqiu⁵⁶⁷⁴,Diao Quanping¹²³⁴,Xin Guang¹²³⁴,Meng Qingling¹²³⁴,Hou Dongyan¹²³⁴

Affiliation:

1. School of Chemistry and Life Science

2. Anshan Normal University

3. Anshan

4. China

5. Department of Chemistry

6. Northeast Normal University

7. Changchun

Abstract

An efficient synthetic route to 3-aroyl-5-formyl-4-halo pyridin-2(1H)-ones has been developed via Vilsmeier cyclization of 2-(ethylthio(arylamino)methylene)-1-alkylbutane-1,3-dione.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA14626C

Reference54 articles.

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4. Pyridin-2(1H)-ones: A Promising Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

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