A switchable peptide sensor for real-time lysosomal tracking
Author:
Affiliation:
1. Key Labs for Advanced Materials and Institute of Fine Chemicals
2. East China University of Science and Technology
3. Shanghai 200237, China
4. Institute for Organic Chemistry
5. University of Duisburg-Essen
6. 45117 Essen, Germany
Abstract
A bis-spiropyran functionalized peptide1, which exhibits good cell-permeability, biocompatibility and low cytotoxicity, has been developed for lysosomal tracking.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC00670D
Reference30 articles.
1. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
2. A Lysosome-Targetable and Two-Photon Fluorescent Probe for Monitoring Endogenous and Exogenous Nitric Oxide in Living Cells
3. Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group
4. Labeling Lysosomes and Tracking Lysosome-Dependent Apoptosis with a Cell-Permeable Activity-Based Probe
5. Signals from the lysosome: a control centre for cellular clearance and energy metabolism
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