On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan-Reference-Cited by-同舟云学术

On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan

Published:2016 Issue:7 Volume:7 Page:4158-4166
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Rose Tristin E.¹²³⁴,Curtin Brice H.¹²³⁴,Lawson Kenneth V.¹²³⁴,Simon Adam¹²³⁴,Houk K. N.¹²³⁴,Harran Patrick G.¹²³⁴

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of California Los Angeles

3. Los Angeles

4. USA

Abstract

Brønsted acid promotes internal cinnamylations of tryptophan to form structurally complex pyrroloindolines within unique collections of ansa-bridged composite macrocycles.

Funder

Division of Graduate Education

Division of Chemistry

National Cancer Institute

National Institute of General Medical Sciences

University of California

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC04612B

Reference54 articles.

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3. The reaction of koshland's protein reagent with tryptophan

4. Chemistry of the modification of tryptophan with 2-hydroxy-5-nitrobenzyl bromide

5. The First Method for Protection−Deprotection of the Indole 2,3-π Bond

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