Enhancement of anti-tumor immune responses induced by ligand-mediated biomimetic Texosomes-Reference-Cited by-同舟云学术

Enhancement of anti-tumor immune responses induced by ligand-mediated biomimetic Texosomes

Published:2016 Issue:61 Volume:6 Page:55819-55824
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Zhongyan¹²³⁴,Chang Shasha¹²³⁴,Zhao Xiuli¹²³⁴,Chen Dawei¹²³⁴,Li Kexin¹²³⁴

Affiliation:

1. School of Pharmacy

2. Shenyang Pharmaceutical University

3. Liaoning Province

4. China

Abstract

In order to overcome the immune tolerance and awake the tumor patients’ self immune response, hTERT-HSP70 as a universal tumor antigen is specifically transferred to dendritic cells by DEC205McAb Texosomes as the carriers of a tumor vaccine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA05444G

Reference28 articles.

1. The use of calcium phosphate nanoparticles encapsulating Toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activation

2. Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study

3. Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase I/II trial

4. hTERT: Another brick in the wall of cancer cells

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1. Further exploring the feasibility of dendritic cells-targeted biomimetic Texosomes as a therapeutic and preventive tumor-vaccine;RSC Advances;2017