The effect of alcohols as vehicles on the percutaneous absorption and skin retention of ibuprofen modified with l-valine alkyl esters-Reference-Cited by-同舟云学术

The effect of alcohols as vehicles on the percutaneous absorption and skin retention of ibuprofen modified with l-valine alkyl esters

Published:2020 Issue:68 Volume:10 Page:41727-41740
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ossowicz Paula¹²³⁴⁵^ORCID,Klebeko Joanna¹²³⁴⁵^ORCID,Janus Ewa¹²³⁴⁵^ORCID,Nowak Anna⁶⁷⁸⁵^ORCID,Duchnik Wiktoria⁶⁷⁸⁵^ORCID,Kucharski Łukasz⁶⁷⁸⁵^ORCID,Klimowicz Adam⁶⁷⁸⁵^ORCID

Affiliation:

1. West Pomeranian University of Technology, Szczecin

2. Faculty of Chemical Technology and Engineering

3. Department of Chemical Organic Technology and Polymeric Materials

4. 71-065 Szczecin

5. Poland

6. Pomeranian Medical University in Szczecin

7. Department of Cosmetic and Pharmaceutical Chemistry

8. 70-111 Szczecin

Abstract

The effect of various alcohols as vehicles on skin permeability was compared for unmodified ibuprofen (IBU) and ion pairs of ibuprofen with l-valine alkyl esters [ValOR][IBU], in which the alkyl chain R was changed from C1 to C8.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06567F

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