Regulation of micropatterned curvature-dependent FA heterogeneity on cytoskeleton tension and nuclear DNA synthesis of malignant breast cancer cells-Reference-Cited by-同舟云学术

Regulation of micropatterned curvature-dependent FA heterogeneity on cytoskeleton tension and nuclear DNA synthesis of malignant breast cancer cells

Published:2023 Issue:1 Volume:11 Page:99-108
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wang Yongtao¹^ORCID,Wang Nana²,Chen Yazhou³,Yang Yingjun⁴^ORCID

Affiliation:

1. School of Medicine, Shanghai University, Shanghai, 200444, China

2. Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China

3. Medical 3D Printing center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450052, China

4. Materials Institute of Atomic and Molecular Science, Shaanxi University of Science and Technology, Xi’an, 710021, China

Abstract

The interfacial heterogeneity of cells was controlled by geometric micropatterns. Polar curvature and heterogeneity could enhance DNA synthesis by BrdU evaluation, related with FA, cytoskeletal force, ezrin expression, and mechanotransduction.

Funder

National Natural Science Foundation of China

Shaanxi University of Science and Technology

Natural Science Foundation of Shaanxi Province

Zhengzhou University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB01774A

Reference51 articles.

1. Distinct epigenetic changes in the stromal cells of breast cancers

2. Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

3. Genomic characterization of metastatic breast cancers

4. Distinct gene expression profiles between primary breast cancers and brain metastases from pair-matched samples

5. Solutions to the Drawbacks of Photothermal and Photodynamic Cancer Therapy

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