Surface defection reduces cytotoxicity of Zn(2-methylimidazole)2 (ZIF-8) without compromising its drug delivery capacity
Author:
Affiliation:
1. Department of Biomedical Engineering
2. Michigan Technological University
3. Houghton, USA
4. Department of Materials Science and Engineering
5. Department of Electrical & Computer Engineering
6. University of Houston
7. Houston, USA
Abstract
Surface defection incurs bond breakage and unsaturated Zn-sites and N-sites on the external surface of ZIF-8 particles. These bonds in turn bind H2O molecules in an aqueous environment, converting ZIF-8 from hydrophobic to hydrophilic.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA24336J
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