Synthesis of novel N-9 substituted 6-(4-(4-propoxyphenyl)piperazin-1-yl)-9H-purine derivatives as inducers of apoptosis in MCF-7 breast cancer cells-Reference-Cited by-同舟云学术

Synthesis of novel N-9 substituted 6-(4-(4-propoxyphenyl)piperazin-1-yl)-9H-purine derivatives as inducers of apoptosis in MCF-7 breast cancer cells

Published:2016 Issue:19 Volume:6 Page:15286-15297
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sunagar Manjunath G.¹²³⁴,Gaonkar Supreet¹²³⁴,Sunagar Santosh G.⁵⁶⁷⁸⁹,Deshapande Narahari¹²³⁴,Belavagi Ningaraddi S.¹²³⁴,Khazi Imtiyaz Ahmed M.¹²³⁴

Affiliation:

1. Department of Chemistry

2. Karnatak University

3. Dharwad 580003

4. India

5. Bio-X Institutes

6. Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education)

7. Shanghai Jiao Tong University

8. Shanghai 200240

9. P. R. China

Abstract

A series of N-9 substituted 6-(4-(4-propoxyphenyl)piperazin-1-yl)-9H-purine derivatives (PP05–PP21) were prepared and evaluated for their anticancer activity against a panel of human cancer cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA23242B

Reference21 articles.

1. The Chemodiversity of Purine as a Constituent of Natural Products

2. The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

3. Three Newly Approved Drugs for Chronic Lymphocytic Leukemia: Incorporating Ibrutinib, Idelalisib, and Obinutuzumab into Clinical Practice

4. Clofarabine

5. Nelarabine

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