Enhancing cell-scale performance via sustained release of the varicella-zoster virus antigen from a microneedle patch under simulated microgravity

Author:

Yin Yue1,Yang Junyuan1,Gao Ge1,Zhou Huaijuan2ORCID,Chi Bowen3,Yang Hong Yu4,Li Jinhua1ORCID,Wang Yilong3

Affiliation:

1. School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China

2. Advanced Research Institute of Multidisciplinary Sciences, Beijing Institute of Technology, Beijing 100081, China

3. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

4. College of Materials Science and Engineering, Jilin Institute of Chemical Technology, Jilin City 132022, Jilin Province, China

Abstract

A sustained-release microneedle patch was developed as a durable VZV vaccine delivery system under simulated microgravity, which is also of great significance for preventing general viral infections in space.

Funder

Beijing Institute of Technology Research Fund Program for Young Scholars

Jilin Scientific and Technological Development Program

Beijing Institute of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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