Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole

Author:

Lin Yan12345,Ong Yih Ching12345,Keller Sarah12345ORCID,Karges Johannes12345ORCID,Bouchene Rafika36789ORCID,Manoury Eric36789ORCID,Blacque Olivier10111213ORCID,Müller Joachim14151613,Anghel Nicoleta14151613,Hemphill Andrew14151613,Häberli Cécile1718191320,Taki Aya C.2122232425,Gasser Robin B.2122232425,Cariou Kevin12345ORCID,Keiser Jennifer1718191320,Gasser Gilles12345ORCID

Affiliation:

1. Chimie ParisTech

2. PSL University

3. CNRS

4. Institute of Chemistry for Life and Health Sciences

5. Laboratory for Inorganic Chemical Biology

6. LCC (Laboratoire de Chimie de Coordination)

7. Université de Toulouse

8. UPS

9. INPT

10. Department of Chemistry

11. University of Zurich

12. 8057 Zurich

13. Switzerland

14. Institute of Parasitology

15. University of Bern

16. 3012 Bern

17. Department of Medical Parasitology and Infection Biology

18. Swiss Tropical and Public Health Institute

19. Basel

20. University of Basel

21. Department of Veterinary Biosciences

22. Melbourne Veterinary School

23. Faculty of Veterinary and Agricultural Sciences

24. The University of Melbourne

25. Parkville

Abstract

A series of new ferrocenyl and ruthenocenyl derivatives of the organic drug albendazole have been prepared and their activity against different helminths and protozoans assessed.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

H2020 European Research Council

Agence Nationale de la Recherche

China Scholarship Council

Australian Research Council

University of Melbourne

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference46 articles.

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