Controlled dimerization of artificial membrane receptors for transmembrane signal transduction
Author:
Affiliation:
1. State Key Laboratory of Chemo/Biosensing and Chemometrics
2. College of Biology
3. Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province
4. Hunan University
5. Changsha 410082
Abstract
An artificial transmbrane signal transducer was developed through the chemical input-mediated dimerization of artificial DNA transmembrane receptors and the subsequent activation of a cascade of events inside the vesicles.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Hunan Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00718A
Reference34 articles.
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5. Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation
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