New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders-Reference-Cited by-同舟云学术

New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders

Published:2023 Issue:16 Volume:52 Page:5176-5191
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Gouveia Júnior Florêncio Sousa¹^ORCID,Silveira João Alison de Moraes²³,Holanda Thais Muratori²³,Marinho Aline Diogo³,Ridnour Lisa A.⁴,Wink David A.⁴,de Siqueira Rodrigo José Bezerra²,Monteiro Helena Serra Azul²³,Sousa Eduardo Henrique Silva de¹^ORCID,Lopes Luiz Gonzaga de França¹^ORCID

Affiliation:

1. Laboratory of Bioinorganic Chemistry, Department of Organic and Inorganic Chemistry, Federal University of Ceara, 60455-760, Fortaleza-CE, Brazil

2. Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceara, Coronel Nunes de Melo St., 1127, 60.430-275, Fortaleza-CE, Brazil

3. Drug Research and Development Center (NPDM), Federal University of Ceara, Coronel Nunes de Melo St., 1000, 60.430-275, Fortaleza-CE, Brazil

4. National Cancer Institute, Cancer and Inflammation Program, Frederick, Maryland 21702, USA

Abstract

New ruthenium nitrosyl complexes were synthesized and characterized by spectroscopic techniques, including X-ray absorption. Under selected conditions, they were able to release NO and HNO, which was demonstrated through in vitro cell assays.

Funder

National Institutes of Health

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico

Financiadora de Estudos e Projetos

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00059A