A dual-site controlled pH probe revealing the pH of sperm cytoplasm and screening for healthy spermatozoa-Reference-Cited by-同舟云学术

A dual-site controlled pH probe revealing the pH of sperm cytoplasm and screening for healthy spermatozoa

Published:2021 Issue:17 Volume:9 Page:3662-3665
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Li Xiaoliang¹²³⁴⁵^ORCID,Wu Sixian¹²³⁴⁵,Yu Kangkang⁶⁴⁵,Hou Jianwen¹²³⁴⁵,Jiang Chuan¹²³⁴⁵,Li Kun⁷⁴⁵^ORCID,Chu Zhiwen⁸⁴⁵,Jiang Xiaohui⁹⁴⁵,Yu Xiaoqi⁷⁴⁵^ORCID,Xu Wenming¹²³⁴⁵

Affiliation:

1. Department of Obstetrics/Gynecology, Joint Laboratory of Reproductive Medicine

2. SCU-CUHK, Key Laboratory of Obstetric, Gynaecologic and Paediatric Diseases and Birth Defects of Ministry of Education

3. West China Second University Hospital, Sichuan University

4. Chengdu

5. China

6. Key Laboratory of Bio-Resources and Eco-Environment (Ministry of Education), College of Life Sciences, Sichuan University

7. Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University

8. West China School of Pharmacy, Sichuan University

9. Human Sperm Bank, West China Second University Hospital, Sichuan University

Abstract

A dual-site controlled pH probe was applied to sensitively monitor intracellular pH changes in spermatozoa. And it could observed the intracellular pH of sperm from asthenozoospermia patients was significantly lower than healthy individuals.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB00108F

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