Platinum(iv)-azido monocarboxylato complexes are photocytotoxic under irradiation with visible light-Reference-Cited by-同舟云学术

Platinum(iv)-azido monocarboxylato complexes are photocytotoxic under irradiation with visible light

Published:2021 Issue:30 Volume:50 Page:10593-10607
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Shaili Evyenia¹²³⁴,Romero Marίa J.¹²³⁴⁵,Salassa Luca¹²³⁴⁶^ORCID,Woods Julie A.⁷⁸⁹¹⁰⁴,Butler Jennifer S.¹²³⁴,Romero-Canelón Isolda¹²³⁴¹¹^ORCID,Clarkson Guy¹²³⁴^ORCID,Habtemariam Abraha¹²³⁴,Sadler Peter J.¹²³⁴^ORCID,Farrer Nicola J.¹²³⁴¹²^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. Coventry

4. UK

5. Departamento de Didácticas Aplicadas

6. Donostia International Physics Center

7. Photobiology Unit

8. Department of Dermatology and Photobiology

9. Ninewells Hospital

10. Dundee

11. School of Pharmacy

12. Chemistry Research Laboratory

Abstract

Axially-derived platinum(iv) diazido dihydroxido complexes retain dark stability with rapid photoreduction under irradiation with green (517 ± 27 nm) light. Cell uptake is unhindered by overall negative charge at physiological pH (complex 1).

Funder

Wellcome Trust

Cancer Research UK

Engineering and Physical Sciences Research Council

FP7 Ideas: European Research Council

Agencia Estatal de Investigación

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT01730F