Cascade branch migration-triggered strand displacement amplification for specific and sensitive detection of microRNA

Author:

Xie Yaxing12,Hou Yulei1,Yu Yang2,Zhang Jianhong1,Long Jinyan2,Chen Mengqi2,Lang Xueqing2,Yang Xiaolan2ORCID,Chen Hui1ORCID

Affiliation:

1. Clinical Laboratories, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P. R. China

2. Key Laboratory of Medical Laboratory Diagnostics of the Education Ministry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, P. R. China

Abstract

This work, for the first time, combines the cascade branch migration and strand displacement amplification for both specific and sensitive microRNA detection.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing Municipality

Publisher

Royal Society of Chemistry (RSC)

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