Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity-Reference-Cited by-同舟云学术

Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity

Published:2018 Issue:19 Volume:10 Page:9311-9319
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

An Myunggi¹²³⁴,Yu Chunsong¹²³⁴,Xi Jingchao¹²³⁴,Reyes Joyce⁵²³⁴⁶,Mao Guangzhao¹²³⁴,Wei Wei-Zen⁵²³⁴⁶,Liu Haipeng¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical Engineering and Materials Science

2. Wayne State University

3. Detroit

4. USA

5. Department of Oncology

6. Tumor Biology and Microenvironment Program

Abstract

Potent antitumor immunity is induced by intratumoral injection of cytotoxic silica nanoparticles complexed with a STING agonist.

Funder

American Cancer Society

Wayne State University

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C8NR01376D

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2. Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

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