Influence of charge transfer on the isomerisation of stilbene derivatives for application in cancer therapy
Author:
Affiliation:
1. STFC Rutherford Appleton Laboratory
2. Harwell Oxford
3. Didcot OX11 0QX
4. UK
5. School of Environment and Life Sciences
6. University of Salford
7. Salford M5 4WT
Abstract
The photoisomerisation of non-toxictrans-combretastatin CA4 to its cytotoxiccisisomer demonstrates the high potential of this and similar compounds for localised cancer therapy.
Funder
Science and Technology Facilities Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CP/C8CP05375H
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5. Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic Results
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