Thiazolidine-2,4-dione framework containing spiropyrrolidine-oxindole and 1,2,3-triazole scaffold: synthesis, <i>in vitro</i> α-amylase inhibition and <i>in silico</i> studies-Reference-Cited by-同舟云学术

Thiazolidine-2,4-dione framework containing spiropyrrolidine-oxindole and 1,2,3-triazole scaffold: synthesis, in vitro α-amylase inhibition and in silico studies

Published:2023 Issue:11 Volume:47 Page:5399-5412
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Duhan Meenakshi¹,Singh Rahul¹,Devi Meena¹,Sindhu Jayant²^ORCID,Kumar Parvin¹^ORCID,Kumar Sudhir³,Kataria Ramesh⁴^ORCID,Kumar Ashwani⁵,Lal Sohan¹^ORCID,Singh Devender⁶^ORCID

Affiliation:

1. Department of Chemistry, Kurukshetra University, Kurukshetra-136119, India

2. Department of Chemistry, COBS&H, CCS HAU, Hisar-125004, India

3. Department of MBB&B, COBS&H, CCS HAU, Hisar-125004, India

4. Department of Chemistry and Centre for Advance Studies in Chemistry, Panjab University, Chandigarh-160014, India

5. Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana-125001, India

6. Department of Chemistry, Maharshi Dayanand University, Rohtak, Haryana-124001, India

Abstract

This study aimed to synthesize thiazolidine-2,4-dione hybrids followed by evaluating their α-amylase inhibition using in vitro and in silico approaches.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D2NJ05059E

Reference64 articles.

1. Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones

2. Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents

3. New thiazolidine-2,4-dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity

4. An overview on medicinal perspective of thiazolidine-2,4-dione: A remarkable scaffold in the treatment of type 2 diabetes

5. A new series of 2,4-thiazolidinediones endowed with potent aldose reductase inhibitory activity

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of thiazolidine-2,4-dione tethered 1,2,3-triazoles as α-amylase inhibitors: In vitro approach coupled with QSAR, molecular docking, molecular dynamics and ADMET studies;European Journal of Medicinal Chemistry;2024-09

2. Pyrano[2,3-c]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of α-amylase and DPP4 activity;Bioorganic Chemistry;2024-06

3. New Selective Inhibitors of α‐Glucosidase for the Treatment of Type 2 Diabetes Mellitus;Helvetica Chimica Acta;2024-02-29

4. Other medicinal applications;Spirooxindole;2024

5. α‐Amylase Inhibitors Based on Thiazolidinone Skeleton: A Promising Approach in Diabetes Management;ChemistrySelect;2023-12-21