Potential urine biomarkers from a high throughput metabolomics study of severe sepsis in a large Asian cohort-Reference-Cited by-同舟云学术

Potential urine biomarkers from a high throughput metabolomics study of severe sepsis in a large Asian cohort

Published:2015 Issue:124 Volume:5 Page:102204-102209
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liang Qun¹²³⁴⁵,Liu Han⁶⁷⁸,Zhang Tianyu¹²³⁴⁵,Jiang Yan¹²³⁴⁵,Xing Haitao¹²³⁴⁵,Zhang Ai-hua¹²³⁴⁵

Affiliation:

1. ICU Center

2. First Affiliated Hospital

3. School of Pharmacy

4. Heilongjiang University of Chinese Medicine

5. Harbin 150040

6. Simon Fraser University (SFU)

7. Burnaby

8. Canada

Abstract

Non-targeted mass spectrometry was used to characterize peripheral biomarkers associated with the urine metabolome in severe sepsis (SS) patients. This is an efficient and convenient tool for diagnosing and screening of SS in a high-risk population.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19875E

Reference25 articles.

1. Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy

2. Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit

3. Dynamic Changes in Amino Acid Concentration Profiles in Patients with Sepsis

4. Biomarkers in Sepsis

5. Urinary 1H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sepsis biomarkers and diagnostic tools with a focus on machine learning;eBioMedicine;2022-12

2. Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response;Metabolites;2022-04-21

3. A Unique Urinary Metabolic Feature for the Determination of Bladder Cancer, Prostate Cancer, and Renal Cell Carcinoma;Metabolites;2021-09-02

4. High‐throughput metabolomics discovers metabolite biomarkers and insights the protective mechanism of schisandrin B on myocardial injury rats;Journal of Separation Science;2020-12-10

5. Metabolomics approach based on utra‐performance liquid chromatography coupled to mass spectrometry with chemometrics methods for high‐throughput analysis of metabolite biomarkers to explore the abnormal metabolic pathways associated with myocardial dysfunction;Biomedical Chromatography;2020-05-04