Metal-free construction of dihydropyrazino[2,3-<i>b</i>]indoles from 2-aminoacetophenones, isocyanates and 1,2-diamines-Reference-Cited by-同舟云学术

Metal-free construction of dihydropyrazino[2,3-b]indoles from 2-aminoacetophenones, isocyanates and 1,2-diamines

Published:2024 Issue:10 Volume:22 Page:2043-2048
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Fang Jingxi¹,Fang Jiayao¹,Rao Yingbo¹,Qiu Huanyi¹,Pan Zhentao¹^ORCID,Ma Yongmin¹^ORCID

Affiliation:

1. Institute of Advanced Studies and School of Pharmaceutical and Chemical Engineering, Taizhou University, 1139 Shifu Avenue Taizhou, 318000, People's Republic of China

Abstract

A novel metal-free and mild strategy for the construction of dihydropyrazino[2,3-b]indoles in 2-MeTHF as a green solvent at room temperature is described.

Funder

Science and Technology Plan Project of Taizhou

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01967E

Reference45 articles.

1. Interactions of Antiviral Indolo[2,3-b]quinoxaline Derivatives with DNA

2. Synthesis, anticancer and cytostatic activity of some 6H-indolo[2,3-b]quinoxalines

3. 6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities

4. Design and Synthesis of Ellipticinium Salts and 1,2-Dihydroellipticines with High Selectivities against Human CNS Cancers in vitro

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