A Col I and BCP ceramic bi-layer scaffold implant promotes regeneration in osteochondral defects-Reference-Cited by-同舟云学术

A Col I and BCP ceramic bi-layer scaffold implant promotes regeneration in osteochondral defects

Published:2019 Issue:7 Volume:9 Page:3740-3748
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cai Hanxu¹²³⁴,Yao Ya¹²³⁴,Xu Yang¹²³⁴,Wang Qing¹²³⁴,Zou Wen¹²³⁴⁵,Liang Jie¹²³⁴⁵,Sun Yong¹²³⁴^ORCID,Zhou Changchun¹²³⁴,Fan Yujiang¹²³⁴^ORCID,Zhang Xingdong¹²³⁴

Affiliation:

1. National Engineering Research Center for Biomaterials

2. Sichuan University

3. Chengdu 610064

4. P. R. China

5. Sichuan Testing Center for Biomaterials and Medical Devices

Abstract

A new bi-layer scaffold composed of Col I and BCP ceramic was prepared to regenerate osteochondral defect. The result demonstrated the bi-layer scaffold could effectively promote the regeneration of both the cartilage and the subchondral bone layer.

Funder

China Association for Science and Technology

Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA09171D

Reference35 articles.

1. Osteochondral tissue engineering: Current strategies and challenges

2. A new bi-layered scaffold for osteochondral tissue regeneration: In vitro and in vivo preclinical investigations