Confinement size determines the architecture of Ran-induced microtubule networks-Reference-Cited by-同舟云学术

Confinement size determines the architecture of Ran-induced microtubule networks

Published:2021 Issue: Volume: Page:
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Gai Ya¹²³⁴^ORCID,Cook Brian⁵²³⁴,Setru Sagar⁶²³⁴,Stone Howard A.¹²³⁴^ORCID,Petry Sabine⁵²³⁴^ORCID

Affiliation:

1. Department of Mechanical and Aerospace Engineering

2. Princeton University

3. Princeton

4. USA

5. Department of Molecular Biology

6. Lewis-Sigler Institute of Integrative Genomics

Abstract

By using microfluidics to encapsulate mitotic extracts, we show that both microtubule nucleation and physical confinement play critical roles in determining the spatial organization of the microtubule cytoskeleton.

Funder

David and Lucile Packard Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SM/D1SM00045D

Reference51 articles.

1. Mechanisms of Mitotic Spindle Assembly

2. Acentrosomal spindle assembly and chromosome segregation during oocyte meiosis

3. Mechanisms of plant spindle formation

4. Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts

5. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

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1. Branched microtubule nucleation and dynein transport organize RanGTP asters in Xenopus laevis egg extract;Molecular Biology of the Cell;2024-01-01

2. The Mitotic Spindle as Active Machinery;Out-of-equilibrium Soft Matter;2023-03-24

3. How Microtubules Build the Spindle Branch by Branch;Annual Review of Cell and Developmental Biology;2022-10-06