Transitioning organic synthesis from organic solvents to water. What's your E Factor?

Author:

Lipshutz Bruce H.123,Ghorai Subir456

Affiliation:

1. Department of Chemistry & Biochemistry

2. University of California

3. Santa Barbara, USA

4. New Product Research & Development

5. Sigma-Aldrich Chemical Corp.

6. Milwaukee, USA

Abstract

A review, highlighting use of nanoreactors in water composed of “designer” surfactants as alternatives to organic solvents.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference119 articles.

1. The E Factor: fifteen years on

2. Toward a ‘reagent-free’ synthesis

3. P. Dunn , R.Henderson , I.Mergelsberg and A.Wells , Collaboration to Deliver a Solvent Selection Guide for the Pharmaceutical Industry Moving towards Greener Solvents for Pharmaceutical Manufacturing - An Industry Perspective , ACS Green Chemistry Institute® Pharmaceutical , College Park, Maryland . June 23–25, 2009 . http://acs.confex.com/acs/green09/recordingredirect.cgi/id/510

4. Water in Organocatalytic Processes: Debunking the Myths

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