Exploring mutasynthesis to increase structural diversity in the synthesis of highly oxygenated polyketide lactones-Reference-Cited by-同舟云学术

Exploring mutasynthesis to increase structural diversity in the synthesis of highly oxygenated polyketide lactones

Published:2014 Issue:28 Volume:12 Page:5304-5310
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Botubol-Ares J. M.¹²³⁴,Durán-Peña M. J.¹²³⁴,Macías-Sánchez A. J.¹²³⁴,Hanson J. R.⁵⁶⁷,Collado I. G.¹²³⁴,Hernández-Galán R.¹²³⁴

Affiliation:

1. Departamento de Química Orgánica

2. Facultad de Ciencias

3. Universidad de Cádiz

4. Puerto Real, Spain

5. Department of Chemistry

6. University of Sussex

7. Brighton, UK

Abstract

Four new highly oxygenated 11-membered lactones (11–14) were synthesized by a combination of metabolic engineering techniques with complex chemical substrate synthesis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00717D

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