Water as the reaction medium in organic chemistry: from our worst enemy to our best friend

Author:

Cortes-Clerget Margery123ORCID,Yu Julie4567ORCID,Kincaid Joseph R. A.4567ORCID,Walde Peter89103ORCID,Gallou Fabrice123ORCID,Lipshutz Bruce H.4567ORCID

Affiliation:

1. Chemical & Analytical Development

2. 4056 Basel

3. Switzerland

4. Department of Chemistry & Biochemistry

5. University of California

6. Santa Barbara

7. USA

8. Department of Materials

9. ETH Zurich

10. Zurich

Abstract

A review that highlights water as the logical reaction medium in which organic chemistry can be practiced. The key roles that water can play in directing reaction outcomes, including impacting mechanistic features, are discussed using selected examples.

Funder

National Science Foundation

Novartis

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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