Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis via Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in rats-Reference-Cited by-同舟云学术

Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis via Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in rats

Published:2021 Issue:13 Volume:12 Page:6001-6013
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

El Badawy Shymaa A.¹²³⁴⁵^ORCID,Ogaly Hanan A.⁶⁷⁸⁹¹⁰^ORCID,Abd-Elsalam Reham M.¹¹²³⁴⁵^ORCID,Azouz Asmaa A.¹²³⁴⁵

Affiliation:

1. Department of Pharmacology

2. Faculty of Veterinary Medicine

3. Cairo University

4. Giza

5. Egypt

6. Department of Chemistry

7. College of Science

8. King Khalid University

9. Abha

10. Saudi Arabia

11. Department of Pathology

Abstract

The present study investigated the gastroprotective activity of benzyl isothiocyanates (BITC) on indomethacin (IND)-induced gastropathy via its antioxidant, anti-inflammatory, and anti-apoptotic activities.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO00645B

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3. Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases