Construction of engineered 3D islet micro-tissue using porcine decellularized ECM for the treatment of diabetes

Author:

Wang Xiaocheng12,Jin Lijuan23,Liu Wenyu23,Stingelin Lukas2,Zhang Pan1,Tan Zhikai23ORCID

Affiliation:

1. Department of Infectious Diseases, Third Xiangya Hospital, Central South University, Changsha, 410008, China

2. College of Biology, Hunan University, Changsha, 410082, China

3. Shenzhen Institute, Hunan University, Shenzhen, 518000, China

Abstract

3D islet micro-tissues are fabricatied using porcine decellularized ECM, which could be used not only for islet micro-tissue culture in vitro, but also have great promise for islet transplantation for the treatment of diabetes.

Funder

Key Project of Research and Development Plan of Hunan Province

Fudan University

Shanghai Key Laboratory of Peripheral Nerve and Microsurgery

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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