Protonation states at different pH, conformational changes and impact of glycosylation in synapsin Ia
Author:
Affiliation:
1. H.E.J.
2. Research Institute of Chemistry
3. International Center for Chemical and Biological Sciences
4. University of Karachi
5. Karachi 75270
6. Dr. Panjwani Center for Molecular Medicine and Drug Research
7. Pakistan
Abstract
Synapsin I (SynI) is the most abundant brain phosphoprotein present at presynaptic terminals that regulates neurotransmitter release, clustering of synaptic vesicles (SVs) at active zones, and stimulates synaptogenesis and neurite outgrowth.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP00531F
Reference50 articles.
1. The Presynaptic Active Zone
2. Functional distribution of synapsin I in human sperm
3. The synapsins: Key actors of synapse function and plasticity
4. Synapsin I Controls Synaptic Maturation of Long-Range Projections in the Lateral Amygdala in a Targeted Selective Fashion
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