Photocatalytic intramolecular radical cyclization involved synergistic SET and HAT: synthesis of 3,3-difluoro-γ-lactams
Author:
Affiliation:
1. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals
2. Zhejiang University of Technology
3. Hangzhou
4. PR China
5. College of Pharmaceutical Sciences
Abstract
A mild and metal-free protocol for visible-light induced intramolecular radical cyclization of N-allyl(propargyl)-2-bromo-2,2-difluoro-N-arylacetamide has been developed.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Zhejiang Province
Zhejiang University of Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01188F
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