Zinc-catalyzed asymmetric nitrooxylation of β-keto esters/amides with a benziodoxole-derived nitrooxy transfer reagent

Author:

Li Bin1234,Cheng Xuan1234,Guan Zhen-Yu1234,Li Si-Yuan1234,Huo Tao1234,Cheng Guo1234,Fan Yan-Hui1234,Zhou Fang-Shuai1234,Deng Qing-Hai1234ORCID

Affiliation:

1. The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials

2. Shanghai Normal University

3. Shanghai 200234

4. P. R. China

Abstract

Zinc-catalyzed asymmetric nitrooxylation to afford a series of α-nitrooxy β-keto esters/amides in high yields and with low to moderate enantioselectivities has been disclosed.

Funder

Shanghai Engineering Technology Research Center

National Natural Science Foundation of China

Shanghai Rising-Star Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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