Hydrogel-incorporating unit in a well: 3D cell culture for high-throughput analysis

Author:

Yu Yeong Jun12345,Kim Young Hye123,Na Kyuhwan6573ORCID,Min Seo Yun123,Hwang Ok Kyung8931011,Park Da Kyeong123,Kim Doo Yeon1213141516,Choi Se Hoon1213141516,Kamm Roger D.17181920ORCID,Chung Seok45736,Kim Jeong Ah1232122ORCID

Affiliation:

1. Biomedical Omics Group

2. Korea Basic Science Institute

3. Republic of Korea

4. Program in Micro/Nano System

5. Korea University

6. School of Mechanical Engineering

7. Seoul 02841

8. New Drug Development Center

9. Osong Medical Innovation Foundation

10. College of Pharmacy and Medical Research Center

11. Chungbuk National University

12. Genetics and Aging Research Unit

13. MassGeneral Institute for Neurodegenerative Disease

14. Massachusetts General Hospital

15. Harvard Medical School

16. Charlestown

17. Department of Mechanical Engineering

18. Massachusetts Institute of Technology

19. Cambridge

20. USA

21. Department of Bio-Analytical Science

22. University of Science and Technology

Abstract

A microchannel-free, 3D cell culture system has a hydrogel-incorporating unit integrated with a multi-well plate. This plate provides better reproducibility in a variety of quantitative biochemical assays and high content-screening (HCS).

Funder

Ministry of Science, ICT and Future Planning

Ministry of Trade, Industry and Energy

Korea Basic Science Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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