Microenvironment-tailored nanoassemblies for the diagnosis and therapy of neurodegenerative diseases

Author:

Low Liang Ee12345,Wang Qiyue12345,Chen Ying12345,Lin Peihua12345,Yang Shengfei12345,Gong Linji678910,Lee Jiyoung12345,Siva Sangeetaprivya P.1112131415,Goh Bey-Hing12345,Li Fangyuan12345,Ling Daishun12345ORCID

Affiliation:

1. Institute of Pharmaceutics

2. College of Pharmaceutical Sciences

3. Zhejiang University

4. Hangzhou

5. P. R. China

6. National Center for Translational Medicine

7. Frontiers Science Center for Transformative Molecules

8. School of Chemistry and Chemical Engineering

9. Shanghai Jiao Tong University

10. Shanghai 200240

11. Chemical Engineering Discipline

12. School of Engineering

13. Monash University Malaysia

14. 47500 Bandar Sunway

15. Malaysia

Abstract

This review discussed the design of stimuli-responsive nanoassemblies that can effectively penetrate BBB and interfere with various pathological factors of NME for effective diagnosis and therapy of neurodegenerative disease.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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