Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors

Author:

Hackbarth Steffen12345ORCID,Islam Waliul678910,Fang Jun1112131410,Šubr Vladimír15161718ORCID,Röder Beate12345,Etrych Tomáš15161718ORCID,Maeda Hiroshi192010

Affiliation:

1. Photobiophysics

2. Institute of Physics

3. Humboldt University of Berlin

4. 12489 Berlin

5. Germany

6. Department of Microbiology

7. Graduate School of Medical Sciences

8. Kumamoto University

9. Kumamoto 860-8556

10. Japan

11. Laboratory of Microbiology and Oncology

12. Faculty of Pharmaceutical Sciences

13. Sojo University

14. Kumamoto 860-0082

15. Institute of Macromolecular Chemistry

16. Czech Academy of Sciences

17. 16206 Prague

18. Czech Republic

19. BioDynamics Research Foundation

20. Kumamoto 862-0954

Abstract

Extracorporeal measurements through the skin achieve sufficient SNR to analyze 1O2 kinetics and evaluate PDT efficiency.

Funder

Japan Society for the Promotion of Science

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

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