Asymmetric cross- and self-aldol reactions of aldehydes in water with a polystyrene-supported triazolylproline organocatalyst
Author:
Affiliation:
1. Institute of Chemical Research of Catalonia (ICIQ)
2. The Barcelona Institute of Science and Technology
3. 43007 Tarragona
4. Spain
5. Departament de Química Orgànica
Abstract
A PS-immobilized triazolylproline prepared by co-polymerization with full regiocontrol swells in water and catalyzes the enantioselective cross-aldol reaction and the self-aldol reaction of aldehydes under essentially neat conditions with excellent stereocontrol.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/GC/C6GC00792A
Reference64 articles.
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4. G. Guillena , in Modern Methods in Stereoselective Aldol Reactions, ed. R. Mahrwald, Wiley-VCH, 2013, pp. 155–268
5. Catalytic asymmetric aldol reactions in aqueous media – a 5 year update
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