Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy-Reference-Cited by-同舟云学术

Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

Published:2020 Issue:21 Volume:8 Page:4620-4626
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Jin Shuiling¹²³^ORCID,Weng Lanling¹²³⁴⁵,Li Zhi⁶⁷⁸³,Yang Zhenzhen¹²³⁴⁵,Zhu Lili¹²³⁴⁵,Shi Jianxiang⁴⁵²³,Tang Wenxue⁴⁵²³⁹,Ma Wang¹²³,Zong Hong¹²³,Jiang Wei¹²³⁴⁵

Affiliation:

1. Department of Oncology, the First Affiliated Hospital of Zhengzhou University

2. Zhengzhou

3. China

4. Academy of Medical Science

5. Zhengzhou University

6. Department of General Surgery

7. Henan Cancer Hospital & Affiliated Cancer Hospital of Zhengzhou University

8. Zhengzhou 450008

9. Center for Precision Medicine, the Second Affiliated Hospital of Zhengzhou University

Abstract

Chemodynamic therapy (CDT) has been critically challenged by insufficient H₂O₂ in cancer tissues and inefficient reactive oxygen species (ROS) production.

Funder

National Natural Science Foundation of China

Education Department of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/D0TB00357C

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1. Hydrogen peroxide overproduced in breast cancer cells can serve as an anticancer prodrug generating apoptosis-stimulating hydroxyl radicals under the effect of tamoxifen-ferrocene conjugate

2. Antiferromagnetic Pyrite as the Tumor Microenvironment-Mediated Nanoplatform for Self-Enhanced Tumor Imaging and Therapy