Ultrasensitive detection of disease biomarkers using an immuno-wall device with enzymatic amplification-Reference-Cited by-同舟云学术

Ultrasensitive detection of disease biomarkers using an immuno-wall device with enzymatic amplification

Published:2019 Issue:15 Volume:144 Page:4589-4595
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Nishiyama Keine¹²³⁴^ORCID,Kasama Toshihiro⁵⁶⁷⁸⁴^ORCID,Nakamata Seiya¹²³⁴,Ishikawa Koya⁹¹⁰¹¹¹²⁴,Onoshima Daisuke¹³¹¹¹²⁴¹⁴,Yukawa Hiroshi¹³¹¹¹²⁴⁹^ORCID,Maeki Masatoshi¹⁵¹⁶²³⁴^ORCID,Ishida Akihiko¹⁵¹⁶²³⁴^ORCID,Tani Hirofumi¹⁵¹⁶²³⁴,Baba Yoshinobu¹³¹¹¹²⁴⁹,Tokeshi Manabu¹³¹¹¹²⁴¹⁴^ORCID

Affiliation:

1. Graduate School of Chemical Sciences and Engineering

2. Hokkaido University

3. Sapporo 060-8628

4. Japan

5. Department of Bioengineering

6. School of Engineering

7. The University of Tokyo

8. Kawasaki-shi, Kanagawa

9. Department of Biomolecular Engineering

10. Graduate School of Engineering

11. Nagoya University

12. Nagoya 464-8603

13. ImPACT Research Center for Advanced Nanobiodevices

14. Institute of Nano-Life-Systems

15. Division of Applied Chemistry

16. Faculty of Engineering

Abstract

We present a fluorometric sandwich immunoassay for biomarkers utilizing an antibody-modified microfabricated wall and antibody labeled with an enzyme for signal amplification.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN00480G

Reference44 articles.

1. Biomarkers in cancer screening, research and detection: present and future: a review

2. What is a biomarker? Research investments and lack of clinical integration necessitate a review of biomarker terminology and validation schema

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