Intramolecular chaperone-assisted dual-anchoring activation (ICDA): a suitable preorganization for electrophilic halocyclization

Author:

Yang Xihui1ORCID,Gao Haowei1,Yan Jiale1,Zhou Jia12ORCID,Shi Lei1ORCID

Affiliation:

1. School of Science (Shenzhen), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Shenzhen 518055, China

2. Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, China

Abstract

In this study, a catalyst-free and highly efficient approach to access seven types of small-sized, medium-sized, and large-sized heterocyclic units via halocyclization was developed, leveraging the use of suitable preorganization by the ICDA model.

Funder

National Natural Science Foundation of China

Harbin Institute of Technology

Basic and Applied Basic Research Foundation of Guangdong Province

Fundamental Research Funds for the Central Universities

Shenzhen Science and Technology Innovation Program

Publisher

Royal Society of Chemistry (RSC)

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