Towards aspirin-inspired self-immolating molecules which target the cyclooxygenases-Reference-Cited by-同舟云学术

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Towards aspirin-inspired self-immolating molecules which target the cyclooxygenases

Published:2015 Issue:45 Volume:13 Page:11078-11086
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Drake Christopher R.¹²³⁴,Estévez-Salmerón Luis⁵²³⁴⁶,Gascard Philippe⁵²³⁴⁶,Shen Yang⁷⁸⁹¹⁰⁴,Tlsty Thea D.⁵²³⁴⁶,Jones Ella F.¹²³⁴

Affiliation:

1. Department of Radiology and Biomedical Imaging

2. University of California San Francisco

3. San Francisco

4. USA

5. Department of Pathology

6. Helen Diller Family Comprehensive Cancer Center

7. Department of Electrical and Computer Engineering

8. TEES-AgriLife Center for Bioinformatics and Genomic Systems Engineering

9. Texas A&M University

10. College Station

Abstract

Cyclooxygenase specific self-immolative triggers and their use in activatable fluorescent probes are reported.

Funder

California Breast Cancer Research Program

National Cancer Institute

Avon Foundation for Women

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01805F

Reference25 articles.

1. Amplified release through the stimulus triggered degradation of self-immolative oligomers, dendrimers, and linear polymers

2. Self-immolative linkers in polymeric delivery systems

3. Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents

4. An Off–On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells

5. Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase-2 as Targeted Optical Imaging Agents

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