Development and translation of a paper-based top readout vertical flow assay for SARS-CoV-2 surveillance-Reference-Cited by-同舟云学术

Development and translation of a paper-based top readout vertical flow assay for SARS-CoV-2 surveillance

Published:2022 Issue:7 Volume:22 Page:1321-1332
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Jia Huan¹^ORCID,Miller Eric A.²,Chan Chia Ching¹,Ng Say Yong¹,Prabakaran Mookkan³,Tao Meng³,Cheong Ian Shen-Yi³^ORCID,Lim Sing Mei¹,Chen Ming Wei⁴,Gao Xiaohong⁴^ORCID,R. Abirami¹,McBee Megan E.¹,Preiser Peter R.¹⁴,Sikes Hadley D.¹²^ORCID,Kongsuphol Patthara¹

Affiliation:

1. Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART), 1 CREATE Way, 138602 Singapore

2. Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), 25 Ames Street, Building 66, Cambridge, MA 02139, USA

3. Molecular Pathogenesis Group, Temasek Life Science Laboratory, National University of Singapore, 1 Research Link, 117604 Singapore

4. School of Biological Science (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551 Singapore

Abstract

An enhanced vertical flow assay that allows top readout has been developed and translated into a PoC application for detecting SARS-CoV-2 infection with saliva samples, providing a complementary antigen rapid test for COVID-19 surveillance.

Funder

National Medical Research Council

Temasek Foundation

National Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00073C

Reference47 articles.

1. An interactive web-based dashboard to track COVID-19 in real time