Food-derived cyanidin-3-O-glucoside alleviates oxidative stress: evidence from the islet cell line and diabetic db/db mice-Reference-Cited by-同舟云学术

Food-derived cyanidin-3-O-glucoside alleviates oxidative stress: evidence from the islet cell line and diabetic db/db mice

Published:2021 Issue:22 Volume:12 Page:11599-11610
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ye Xiang¹,Chen Wen¹,Tu Pengcheng¹,Jia Ruoyi¹^ORCID,Liu Yangyang¹,Li Yonglu¹,Tang Qiong¹,Zheng Xiaodong¹^ORCID,Chu Qiang²^ORCID

Affiliation:

1. Department of Food Science and Nutrition, Zhejiang Key Laboratory for Agro-food Processing, Fuli Institute of Food Science, College of Biosystems Engineering and Food Science, National Engineering Laboratory of Intelligent Food Technology and Equipment, Key Laboratory for Agro-Products Postharvest Handling of Ministry of Agriculture, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou 310058, China

2. Tea Research Institute, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou, 310058, China

Abstract

C3G can effectively relieve cellular oxidative stress induced by HG and PA. The antioxidant effect of C3G was achieved by activating mitophagy via the PINK1-PARKIN signaling pathway.

Funder

Science and Technology Program of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02385C

Reference48 articles.

1. Biochemistry and molecular cell biology of diabetic complications

2. The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP–PKA-dependent signaling pathway

3. The update of anthocyanins on obesity and type 2 diabetes: Experimental evidence and clinical perspectives