Desymmetrization of unactivated bis-alkenes via chiral Brønsted acid-catalysed hydroamination-Reference-Cited by-同舟云学术

Desymmetrization of unactivated bis-alkenes via chiral Brønsted acid-catalysed hydroamination

Published:2020 Issue:23 Volume:11 Page:5987-5993
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yu Zhang-Long¹²³⁴⁵,Cheng Yong-Feng¹²³⁴⁵^ORCID,Jiang Na-Chuan¹²³⁴⁵,Wang Jian¹²³⁴⁵,Fan Li-Wen¹²³⁴⁵,Yuan Yue¹²³⁴⁵,Li Zhong-Liang⁶⁴⁵⁷,Gu Qiang-Shuai⁶⁴⁵⁷⁸^ORCID,Liu Xin-Yuan¹²³⁴⁵^ORCID

Affiliation:

1. Shenzhen Grubbs Institute

2. Department of Chemistry

3. Guangdong Provincial Key Laboratory of Catalysis

4. Southern University of Science and Technology

5. Shenzhen 518055

6. Academy for Advanced Interdisciplinary Studies

7. China

8. Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis

Abstract

Highly stereoselective desymmetrising hydroamination of various unactivated alkenes has been achieved using chiral Brønsted acid catalysis via a concerted mechanism.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC00001A

Reference86 articles.

1. Nonenzymatic enantioselective synthesis of all-carbon quaternary centers through desymmetrization

2. Organocatalytic enantioselective desymmetrisation

3. Organocatalytic Enantioselective Desymmetrization of meso-Aziridines and Prochiral Azetidines