Layered rare-earth hydroxides as multi-modal medical imaging probes: particle size optimisation and compositional exploration

Author:

Strimaite Margarita12ORCID,Wells Connor J. R.3ORCID,Prior Timothy J.4ORCID,Stuckey Daniel J.2ORCID,Wells Jack A.2,Davies Gemma-Louise35ORCID,Williams Gareth R.1ORCID

Affiliation:

1. UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK

2. UCL Centre for Advanced Biomedical Imaging, University College London, 72 Huntley Street, London, WC1E 6DD, UK

3. Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ, UK

4. Chemistry, School of Natural Sciences, University of Hull, Kingston Upon Hull, HU6 7RX, UK

5. School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK

Abstract

A detailed study into the synthesis and functional properties of layered rare-earth hydroxides (LRHs) is reported. It is possible to obtain precise control of particle size, and combining Tb and Gd in the LRH allows multi-modal imaging.

Funder

Wellcome Trust

Medical Research Council

Engineering and Physical Sciences Research Council

British Heart Foundation

Publisher

Royal Society of Chemistry (RSC)

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