Active site structure and absorption spectrum of channelrhodopsin-2 wild-type and C128T mutant-Reference-Cited by-同舟云学术

Active site structure and absorption spectrum of channelrhodopsin-2 wild-type and C128T mutant

Published:2016 Issue:6 Volume:7 Page:3879-3891
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Guo Yanan¹²³⁴⁵,Beyle Franziska E.¹²³⁴⁵,Bold Beatrix M.¹²³⁴⁵,Watanabe Hiroshi C.⁶⁷⁸⁹,Koslowski Axel¹⁰¹¹⁵,Thiel Walter¹⁰¹¹⁵,Hegemann Peter¹²¹³¹⁴¹⁵⁵,Marazzi Marco¹²³⁴⁵,Elstner Marcus¹²³⁴⁵

Affiliation:

1. Department of Theoretical Chemical Biology

2. Institute of Physical Chemistry

3. KIT

4. 76131 Karlsruhe

5. Germany

6. Research Center for Advanced Science and Technology

7. The University of Tokyo

8. Tokyo 153-8904

9. Japan

10. Max-Planck-Institut für Kohlenforschung

11. 45470 Mülheim an der Ruhr

12. Institute of Biology

13. Experimental Biophysics

14. Humboldt-Universität

15. D-10115 Berlin

Abstract

We show by extensive ground state and absorption spectra simulations that the channelrhodopsin-2 active site samples three different hydrogen-bonding patterns.

Funder

European Research Council

China Scholarship Council

Deutsche Forschungsgemeinschaft

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00468G

Reference78 articles.