A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection

Author:

Prasad K. Sudhakara1234ORCID,Abugalyon Yousef1234,Li Chunqiang56234,Xu Feng78910ORCID,Li XiuJun123411ORCID

Affiliation:

1. Department of Chemistry

2. University of Texas at El Paso

3. El Paso

4. USA

5. Department of Physics

6. Border Biomedical Research Center

7. Bioinspired Engineering & Biomechanics Center (BEBC)

8. Xi'an Jiaotong University

9. Shaanxi

10. P. R. China

11. Biomedical Engineering

Abstract

Catalytic properties of gold nanoparticles in colour dye degradation are utilized to amplify colorimetric detection signals of a low-cost paper-based immunosensor for instrument-free detection of pancreatic cancer biomarker PEAK1.

Funder

Philadelphia Foundation

University of Texas at El Paso

National Institute of General Medical Sciences

National Institute of Allergy and Infectious Diseases

National Science Foundation

University of Texas System

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference57 articles.

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4. WHO, http://www.who.int/cancer/en/

5. Cancer facts & figures 2017, https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2017/cancer-facts-and-figures-2017.pdf

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