A <i>de novo</i> strategy for the development of a Zn<sup>II</sup>–organic framework based luminescent “switch-on” assay for size-exclusive sensitization of the oxidised form of glutathione (GSSG) over the reduced form (GSH): insights into the sensing mechanism through DFT-Reference-Cited by-同舟云学术

A de novo strategy for the development of a Zn^II–organic framework based luminescent “switch-on” assay for size-exclusive sensitization of the oxidised form of glutathione (GSSG) over the reduced form (GSH): insights into the sensing mechanism through DFT

Published:2023 Issue:11 Volume:25 Page:1626-1636
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Bej Sourav¹²^ORCID,Das Riyanka¹²^ORCID,Kundu Debojyoti¹²,Pal Tapan K.³^ORCID,Banerjee Priyabrata¹²^ORCID

Affiliation:

1. Surface Engineering & Tribology Group, CSIR-Central Mechanical Engineering Research Institute, Mahatma Gandhi Avenue, Durgapur, 713209, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad – 201002, Uttar Pradesh, India

3. Department of Chemistry, Pandit Deendayal Energy University, Gandhinagar – 382426, Gujarat, India

Abstract

The ratio of GSSG to GSH plays a key role as a biomarker for monitoring cellular health thus fuelling extensive ground-breaking research towards the development of robust sensory receptors for continuous monitoring of glutathione concentration.

Funder

Bundesministerium für Bildung und Forschung

Department of Higher Education, Government of West Bengal

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CE/D2CE01600A

Reference46 articles.

1. BODIPY-Based Fluorometric Sensor for the Simultaneous Determination of Cys, Hcy, and GSH in Human Serum

2. Fluorescence detection of glutathione S-transferases in a low GSH level environment